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(2020)\n) and time-to-event\ngeneralized bayesian optimal interval (TITEgBOIN) (Takeda et\nal. (2022) ) designs. 'TITEgBOIN' can\nconduct tasks: run simulations and get operating\ncharacteristics; determine the dose for the next cohort; select\nmaximum tolerated dose (MTD). These functions allow\ncustomization of design characteristics to vary sample size,\ncohort sizes, target dose limiting toxicity (DLT) rates or\ntarget normalized equivalent toxicity score (ETS) rates to\naccount for discrete toxicity score, and incorporate safety\nand/or stopping rules.", "License": "GPL-2", "Encoding": "UTF-8", "RoxygenNote": "7.3.2", "NeedsCompilation": "no", "Author": "Jing Zhu [cre, aut], Jun Zhang [aut], Kentaro Takeda [aut]", "Maintainer": "Jing Zhu ", "Packaged": { "Date": "2026-06-08 06:53:43 UTC", "User": "root" }, "Repository": "https://jingzhuzhuzhu.r-universe.dev", "Date/Publication": "2025-02-26 06:30:01 UTC", "RemoteUrl": "https://github.com/cran/TITEgBOIN", "RemoteRef": "HEAD", "RemoteSha": "bbf573aed933cf5d1e9dc869e05da3ac55b22f94", "MD5sum": "b8522cb8fda3eb5daea5316866c32c67", "_user": "jingzhuzhuzhu", "_type": "src", "_file": "TITEgBOIN_0.4.0.tar.gz", "_fileid": "8e29d15295c639b6d59c57a4db2e51c91c64bf999b0f3f9196ec9ad7d8045d54", "_filesize": 122641, 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