Package: bfboinet 0.1.0

bfboinet: Backfill Bayesian Optimal Interval Design Using Efficacy and Toxicity

The backfill Bayesian optimal interval design using efficacy and toxicity outcomes for dose optimization (BF-BOIN-ET) design is a novel clinical trial design to allow patients to be backfilled at lower doses during a dose-finding trial while prioritizing the dose-escalation cohort to explore a higher dose. The advantages compared to the other designs in terms of the percentage of correct optimal dose (OD) selection, reducing the sample size, and shortening the duration of the trial, in various realistic setting.

Authors:Jing Zhu [cre, aut], Kentaro Takeda [aut]

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bfboinet.pdf |bfboinet.html
bfboinet/json (API)

# Install 'bfboinet' in R:
install.packages('bfboinet', repos = c('https://jingzhuzhuzhu.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

On CRAN:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

1.00 score 2 exports 28 dependencies

Last updated 18 hours agofrom:90883c6e7c. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 19 2024
R-4.5-winOKNov 19 2024
R-4.5-linuxOKNov 19 2024
R-4.4-winOKNov 19 2024
R-4.4-macOKNov 19 2024
R-4.3-winOKNov 19 2024
R-4.3-macOKNov 19 2024

Exports:get.oc.backboinetget.oc.backboinetr

Dependencies:ADGofTestclicolorspacecopuladplyrfansigenericsgluegslIsolatticelifecyclemagrittrMatrixmvtnormnumDerivpcaPPpillarpkgconfigpsplineR6rlangstabledisttibbletidyselectutf8vctrswithr

Readme and manuals

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